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9th Grade Science
Cell Reproduction
3. Cell Division
3.2 Cell Cycle, Growth and regulation
Cell Cycle, Growth and Regulation: Checkpoints, Cyclins, and Cancer
Discover how cells regulate growth through molecular checkpoints and what happens when that regulation breaks down.
What You'll Learn
The cell cycle includes interphase phases G1, S, G2, and mitosis.
Checkpoints monitor DNA integrity before allowing cell cycle progression.
Cyclins and CDKs act as molecular switches driving phase transitions forward.
Checkpoint failures and p53 mutations can lead to uncontrolled cancer growth.
What You'll Practice
1
Students analyze how checkpoint mutations contribute to uncontrolled cell division.
2
Questions test understanding of cyclin, CDK, and p53 regulatory protein roles.
3
Learners match cell cycle phases and key terms to their correct definitions.
Why This Matters
Understanding cell cycle regulation is essential for explaining how organisms grow, repair damage, and how failures in this process lead to diseases like cancer.
This Unit Includes
Practice exercises
Learning resources
Skills
Cell Cycle
Checkpoints
Cyclins
Apoptosis
Cancer Biology
OH Curriculum Aligned